September 21, 2020

Modulation of pancreatic neuroendocrine neoplastic cell fate by autophagy mediated death

Matrood S, de Prisco N, Wissniowski TT, Wiese D, Jabari S, Griesmann H, Wanzel M, Stiewe T, Neureiter D, Klieset E, Mintziras I, Buchholz M, Bartsch DK, Gennarino VA and Di Fazio P.​

Neuroendocrinology, Sep 21 2020, accepted.

September 01, 2020

miR760 regulates ATXN1 levels via interaction with its 5' untranslated region.

Nitschke L, Tewari A, Coffin SL, Xhako E, Pang K, Gennarino VA, Johnson JL, Blanco FA, Zhandong L, Zoghbi HY.

Genes & Development, Sep 1;34(17-18):1147-1160.

April 07, 2020

Pumilio proteins utilize distinct regulatory mecchanisms to achieve complementary functions required for pluripotency and embryogenesis

Uyhazi KE, Yang Y, Liu N, Qi H, Huang XA, Mark W, Weatherbee SD, de Prisco N, Gennarino VA, Song X, Lin H.

Proc Natl Acad Sci U S A. Apr 7;117(14):7851-7862.

August 22, 2019

Loss of Ataxin-1 Potentiates Alzheimer's Pathogenesis by Elevating Cerebral BACE1 Transcription.

October 16, 2018

RBM17 Interacts with U2SURP and CHERP to Regulate Expression and Splicing of RNA-Processing Proteins

De Maio A*, Yalamanchili HK*, Adamski CJ, Gennarino VA, Liu Z, Qin J, Jung SY, Richman R, Orr H, Zoghbi HY. (*Contributed equally).

Cell Reports, Oct 16; 25:726-736. 

February 22, 2018

A mild PUM1 mutation is associated with adult-onset ataxia, whereas haploinsufficiency causes developmental delay and seizures.

Gennarino VA†, Palmer EE, McDonell LM, Wang L, Adamski CJ, Koire A, See L, Chen CA, Schaaf CP, Rosenfeld JA, Panzer JA, Moog U, Hao S, Bye A, Kirk EP, Stankiewicz P, Breman AM, McBride A, Kandula T, Dubbs HA, Macintosh R, Cardamone M, Zhu Y, Ying K, Dias KR, Cho MT, Henderson LB, Baskin B, Morris P, Tao J, Cowley MJ, Dinger ME, Roscioli T, Caluseriu O, Suchowersky O, Sachdev RL, Lichtarge O, Tang J, Boycott KM, Holder JL, and Zoghbi HY†.  (Corresponding authors).

Recommended by T. Hall and A. Durr in F1000Prime.

Commented on Epilepsy Curr. 2019 Mar-Apr;19(2):122-123.

Cell, Feb 22; 172:924-936.

August 27, 2015

NUDT21-spanning CNVs lead to neuropsychiatric disease and altered MeCP2 abundance via alternative polyadenylation.

Gennarino VA*, Alcott CA*, Chen CA, Chaudhury A, Rosenfeld JA, Parikh S, Wheless JW, Roeder ER, Horovitz DDG, Roney EK, Smith JL, Cheung SW, Li W, Nailson JR, Schaaf CP, Zoghbi HY. (*Contributed equally).

eLife Aug 27;4. doi: 10.7554/eLife.10782.

March 12, 2015

Pumilio1 Haploinsufficiency Leads to SCA1-like Neurodegeneration by Increasing Wild-Type Ataxin1 Levels.

Gennarino VA, Singh RK, White JJ, De Maio A, Han K, Kim JY, Jafar-Nejad P, di Ronza A, Kang H, Sayegh LS, Cooper TA, Orr HT, Sillitoe RV and Zoghbi HY. This paper was highlighted in an ALZ forum press release.

Cell, Mar 12;160(6):1087-98.

April 01, 2014

Fragile X-like behaviors and abnormal cortical dendritic spines in Cytoplasmic FMR1-interacting protein 2-mutant mice.

Han K, Chen H, Gennarino VA, Richman R, Lu H, and Zoghbi HY. 

Human Molecular Genetics, Apr 1;24(7):1813-23.

March 01, 2013

Human-specific regulation of MeCP2 levels in fetal brains by microRNA miR-483-5p.

Han K*, Gennarino VA*, Lee Y, Pang K, Hashimoto-Torii K, Choufani S, Raju CS, Oldham MC, Weksberg R, Rakic P, Liu Z, and Zoghbi HY. (*Contributed equally). This paper was selected for the journal cover.

Genes & Development, Mar 1;27(5):485-90.

June 22, 2012

Identification of microRNA-regulated gene networks by expression analysis of target genes.

Gennarino VA, D’angelo G, Dharmalingam G, Fernandez S, Russolillo G, Sanges R, Mutarelli M, Belcastro V, Ballabio A, Verde P, Sardiello M, Banfi S. Website:

Genome Research, Jun;22(6):1163-72. Epub 2012 Feb 24.

July 01, 2011

HOCTAR database: a unique resource for microRNA target prediction.

Gennarino VA†, Sardiello M, Mutarelli M, Dharmalingam G, Maselli V, Lago G and Banfi S. (Corresponding author). Website:

Gene, Jul 1;480(1-2):51-8. Epub 2011 Mar 22.

December 11, 2010

miRNeye: a microRNA expression atlas of the mouse eye.

Karali M, Peluso I, Gennarino VA, Bilio M, Verde R, Lago G, Dollé P, Banfi S. 

BMC Genomics, 2010 Dec 11:715.

March 04, 2010

Promiscuity of enhancer, coding and non-coding transcription functions in ultraconserved elements.

Licastro D*, Gennarino VA*, Petrera F, Sanges R, Banfi S§ and Stupka E§. (*Contributed equally).

BMC Genomics, 2010 Mar 4;11:151.

October 30, 2009

UTRdb and UTRsite (release 2010): a collection of sequences and regulatory motifs of the untranslated regions of eukaryotic mRNAs.

Grillo G, Turi A, Licciulli F, Mignone F, Liuni S, Banfi S, Gennarino VA, Horner DS, Pavesi G, Picardi E, Pesole G. 

Nucleic Acids Research, 2010 Jan;38 (Database issue):D75-80. Epub 2009 Oct 30.

July 24, 2009

A gene network regulating lysosomal biogenesis and function.

Sardiello M, Palmieri M, di Ronza A, Medina DL, Valenza M, Gennarino VA, Di Malta C, Donaudy F, Embrione V, Polishchuk RS, Banfi S, Parenti G, Cattaneo E, Ballabio A. F1000Prime recommended.

Science, Jul 24;325(5939):473-7. Epub 2009 Jun 25.

March 19, 2009

MicroRNA target prediction by expression analysis of host genes.

Gennarino VA, Sardiello M, Avellino R, Meola N, Maselli V, Anand S, Cutillo L, Ballabio A and Banfi S. Website:

Genome Research, Mar;19(3):481-90. Epub 2008 Dec.

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Reviews and Book Chapters

November 04, 2009

MicroRNAs and genetic diseases.

Meola N, Gennarino VA and Banfi S. Pathogenetics Review, 2009 Nov 4;2(1):7.

March 01, 2006

Indagini biomolecolari su ceppi di Salmonella isolati da alimenti con riferimento all'antibiotico resistenza

Attanzio A. & Gennarino VA. Chirone. Anno XII – n. 1 – March 2006:14-15.

March 01, 2006

Studio molecolare di nuovi ceppi di Attinomiceti produttori di antibiotici

Gennarino VA. Chirone. Anno XII – n. 1 – March 2006: 17-18.

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